Sunday, 17th February 40th Annual Lorne Genome Conference 2019

Acknowledgment of Country - Marnie Blewitt 

• Viral Noncoding RNAs: Diversity in Form and Function - Joan Steitz

Julian Wells Medallist: Patick Tam

Medal presented by Vincent Harley

• Julian Wells Medallist Presentation - Patrick Tam
• Redefining the nucleosomal architecture of  active and inactive promoters in the context of cellular plasticity and cancer  - David Tremethick
• The Medical Genome Reference Bank: Whole genomes and phenotype of 2,570 healthy elderly - Mark Pinese
• Erasing epigenetic memory: Understanding the kinetics and specificity of active DNA demethylation - Tim Hore
• Lonely single-stranded DNA seeks RNA … - Jane E.A. Reid
• PHF3 binds RNA polymerase II via the SPOC domain and regulates transcription of neuronal genes - Dea Slade
• Using long read sequencing to detect imprinted DNA methylation - Quentin Gouil
• Transgenerational epigenetic inheritance is a complex, multi-step process. - Alyson Ashe

• Cell type prediction at single-cell resolution - Jose Alquicira
• Characterisation of NHL-2 in small RNA pathways of Caenorhabditis elegans. - Joshua Anderson
• The Cell Landscape in Stemformatics - Paul W Angel
• Functional genomics of the retina - insight through transcriptomics - Brendan R. E. Ansell
• The SPOC domain: A novel reader of the CTD code - Lisa-Marie Appel
• Using protein structure and function information to predict and understand variant pathogenicity - David B Ascher
• Late onset Pompe disease: rescue of acid alpha-glucosidase expression by splice modification - May T Aung-Htut
• Assessing the biological signal of different RNA fractions for computational deconvolution of healthy tissues - Francisco Avila Cobos
• Planting ideas for medicine : Use of Arabidopsis as a model to study genetics of triplet repeat expansions - Sureshkumar Balasubramanian
• Enhancer reprogramming overcomes pervasive non-genetic drug resistance in AML - Charles C Bell
• H3.3S31ph is important for telomeres heterochromatin maintenance in ES cells - Vinod Benjamin
• Glucocorticoid Induced Leucine Zipper is a threshold setter for CD8+ T cell activation and differentiation  - Taylah Bennett
• Diagnosing Fusion Genes in Cancer Using Targeted RNA Sequencing - James Blackburn
• Investigating the potential use of RNA polymerase 1 transcription inhibitors in the treatment of MDS - Daniela P Borges
• Koala MHC: Perks of a PacBio Genome - Parice A Brandies
• The Grainyhead-like 2/Zeb1 axis maintains the balance between epithelial and mesenchymal cells during palate closure. - Marina R Carpinelli
• Molecular mechanism of L1 retrotransposon activation. - Patricia Carreira
• The Intercellular Tight Junction and Spontaneous Coronary Artery Dissection. - Gulrez Chahal
• A putative novel enhancer RNA regulates the expression of Gata3 - Wing Fuk Chan
• PERIPHERAL MONITORING OF NEURODEGENERATION IN FRONTOTEMPORAL DEMENTIA AND HEALTHY CONTROLS USING CELL-FREE DNA METHYLATION - Zac Chatterton
• Characterisation of UBF1-like HMG-box proteins in D. melanogaster. - Hyung-Wook Choi
• Stemformatics: visualise and download curated stem cell data - Jarny Choi
• Electron microscopy of the human telomerase enzyme complexElectron microscopy of the human telomerase enzyme complex - Scott Cohen
• Histone acetyltransferase p300 acetylates histone variant H2A.Z preferentially at H4 acetylated nucleosomes. - Yolanda Colino-Sanguino
• The C. elegans TRIM protein NHL-2 and its role in the let-7 miRNA pathway - Rhys Colson
• Expansion of an ATTTC short tandem repeat is a frequent cause of familial adult myoclonic epilepsy  - Mark A Corbett
• Accumulation of heterozygous DNA methylation changes generates new epialleles in clonal apple tree lineages - Peter A Crisp
• Human and mouse FGF9 mutations affect male sex determination - Brittany Croft
• Looking for genes where the sun don't shine: the genetics of bowel symptoms and function - Mauro D'Amato
• Evaluation of the GATK Best-Practice Workflow for Clinical Whole Genome Sequencing  - Glenn D'Cunha
• Analysis of novel sex biased long non-coding RNA candidates in egg laying mammals. - Tasman Daish
• Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans - Carolyn de Graaf
• Profiling the chromatin landscape of the Drosophila mushroom body - Caroline Delandre
• Impact of varying cadmium concentration on gene expression and reproduction in  E. fetida - Panchamee Ms Dharmadasa
• ­Context is all - Progesterone receptor-chromatin binding properties and implications on tissue-specific gene expression in mouse reproductive tissues - Thao D Dinh
• Consequences of Altered DNA Methylation on DNA Replication Timing - Qian Du
• Deep Convolutional Neural Networks for Nanopore Signal Processing - Tansel Ersavas
• Reference-free reconstruction and error correction of transcriptomes from Nanopore long-read sequencing - Eduardo Eyras
• The functional and immunogenic impacts of RNA-processing alterations in MLL-rearranged infant acute leukemia - Eduardo Eyras
• Control of cell competition by cell shape regulators in tissue development and cancer - Natasha Fahey-Lozano
• CDK12 and 13 regulate RNA Pol II transcription elongation rates - Zheng Fan
• The Role of Planar Cell Polarity in the Initiation of Prostate Cancer - Andrew W Farrell
• Exploring dynamics of non-genomic resistance in AML at the single-cell level - Katie A Fennell
• SquiggleKit: A toolkit for manipulating nanopore signal data - James M Ferguson
• Splicing conservation signals in plant long non-coding RNAs - Selene L Fernandez-Valverde
• RNA polymerase I therapy: the second generation  - Rita Ferreira
• Unlocking somatic SNV and CNA calling with RNA-Seq - Christoffer Flensburg
• Biooorthogonal RNA labelling in Caenorhabditis elegans - Natalya Frolows
• Systematic mapping of molecular interactions within the epigenetic modifier complex PRC2 provides a mechanistic framework for its functional diversity - Emma H Gail
• Characterising functional genetic variation in Island Southeast Asia - Irene Gallego Romero
• Multi-level chromosomal reorganization underlying activation of human T cells - Naiara Garcia Bediaga
• Bona fide DNA methylation readers FOXK1/2 participate in cell cycle regulation and are required for vertebrate embryogenesis - Michael Geng
• Genome-wide loss of function screens to determine the molecular mechanism(s) underlying the nucleolar surveillance response - Amee J George
• Reprogramming activates retrotransposons in mouse induced pluripotent stem cells - Patricia Gerdes
• Histone acetyltransferase HBO1 regulates endothelial cell gene expression during angiogenesis - Zoe L Grant
• Elk1 in Congenital and Late Onset Cardiac Disease: at the Heart of the Matter - Jeannette JCH Hallab
• A functional genomics approach to identify novel analgesic targets - Zina Hamoudi
• Measuring alternative polyadenylation from single cell RNA-seq with precision weights - Paul Harrison
• Enzymatic Methyl-Seq: Next Generation Methylomes - Margaret R Heider
• Improved genome assembly of the tammar wallaby provides a new opportunity to analyze X chromosome evolution in mammals - Thomas N Heider
• Genome-wide analysis of DNA methylation in samples from the Genotype-Tissue Expression (GTEx) project - Peter F Hickey
• Mapping histone variant H2A.B post translational modifications and its interactome in cancer context - Tanya Soboleva
• QuickExtract- Fast & Easy DNA Extractions For End-point Genotyping PCR Applications - Joy Kang
• Molecular Beacons as a Tool for Visualising Random Autosomal Monoallelic Expression of GHR in Human Lymphoblasts - Niall P Keegan
• Unlocking female ES cells for research - Andrew Keniry
• Nerve injury drives a heightened state of vigilance and neuropathic sensitisation in Drosophila - Thang M Khuong
• Mispriming of reverse transcription at GAA repeats masks genuine transcript truncations induced by triplet repeat expansions in eukaryotes - Calvin A Kraupner-Taylor
• Dissecting the pleiotropic function of whirlin in the mammalian system. - Heena V Lad
• New Direct Targets of JAK-STAT signalling which underpin human myeloproliferative neoplasms (MPNs) - Charlene Lam
• The role of the piRNA pathway in ovarian and prostate cancer progression - Eunice Lee
• Loss of ATRX in Sertoli cells leads to DNA double strand breaks at a single PML nuclear body - Nayla Leon
• H3K27ME3 RESTRAINS CELLULAR SUPPORT PROCESSES REQUIRED FOR T CELL DIFFERENTIATION - Jasmine Li
• Systematic Functional Identification of Cancer Multi-Drug Resistance Genes - Man Tat Lau
• Connecting the dots of RNA modifications and small RNA profiles in arabidopsis thaliana  - Pei Qin Ng